Lung ventilation strategies and regional lung inflammation
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چکیده
منابع مشابه
Lung ventilation strategies and regional lung inflammation
Protective mechanical ventilation is currently accepted as a key strategy for the management of acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome. The study by de Prost and colleagues in the current issue of Critical Care provides new insights into the impact of ventilation strategies on pulmonary function, gas exchange, and regional cellular metabolic activi...
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The application of the independent lung ventilation (ILV) in adults has been described by Carlon and co-workers in 1978 and subsequently by other investigators. In 1983 Hedenstierna and coworkers using a bilumen tube suitable for prolonged intubation, and two Servo Ventilator 900 B (Siemens) adapted for synchronization, treated a wide range of clinical conditions. Following this experience, the...
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provided the original work is properly cited. CC Hypoxemia and acute lung injury (ALI) are major concerns with one-lung ventilation (OLV) during thoracic surgery. Hypoxemia is usually the result of alveolar hypoventilation and an increasing shunt fraction, whereas ALI is caused by ventilatory stress (volutrauma, atelectrauma, and barotrauma), reexpansion pulmonary injury, and the lung surgery i...
متن کاملNumerical study of variable lung ventilation strategies
Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths. While it may seem intuitive that lungs may benefit from unvarying and stable ventilation pressure strategy, recently it has been reported that variable lung ventilation is advantageous. In this study, we analyze the mean tidal vo...
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BACKGROUND Lung derecruitment is common during general anesthesia. Mechanical ventilation with physiological tidal volumes could magnify derecruitment, and produce lung dysfunction and inflammation. The authors used positron emission tomography to study the process of derecruitment in normal lungs ventilated for 16 h and the corresponding changes in regional lung perfusion and inflammation. M...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2013
ISSN: 1364-8535
DOI: 10.1186/cc12881